The vaginal microbiota in women health and disease : current understanding and future perspectives : a review

Abstract

Vaginal Microbiota varies within individuals and between human populations. Colonization by Lactobacillus in the female genital tract is thought to be critical for maintaining genital health. Nevertheless, little is known about how genital microbiota influence host immune function and modulate disease susceptibility. This article discusses the advancement of new strategies for disease diagnosis and personalized treatments to promote health and improve the quality of women’s lives. Previous research on the use of vaginal products for sexual intercourse available over the counter used by women has primarily focused on gels, creams and ointments composed by natural origin drugs/excipients and applied by means of an applicator. General concerns and misconceptions related to use of vaginal products were rare. More research is needed from the medical community to guide women clarifying therapeutic outcomes of vaginal products.