Please use this identifier to cite or link to this item: https://hdl.handle.net/10321/3429
Title: A brief review of secondary plant metabolites as anticancer agents
Authors: Mohanlall, Viresh
Naicker, Leeann
Keywords: Anticancer;Secondary metabolites;Topotecan;Etoposide;Vincristine
Issue Date: 18-May-2020
Publisher: COJ Reviews & Research
Source: Mohanlall, V. and Naicker, L. 2020. A brief review of secondary plant metabolites as anticancer agents. COJ Rev & Res. 2(4): 1-5. Available: doi:10.31031/COJRR.2020.02.000545
Journal: COJ Rev & Res, Vol. 2, Issue 4 
Abstract: 
Plants have provided a source of medicine from the beginning of human history and are the core of modern medicine. Moreover, plant-based drug discovery has led to the development of various anticancer drugs
(such as vincristine, vinblastine, etoposide, paclitaxel, camptothecin, topotecan and irinotecan). The use of botanical, photochemical, biological and molecular techniques have facilitated the discovery of novel
secondary metabolites from native and indigenous plants that can inhibit the human topoisomerase II enzyme (target for anticancer drugs) and kill cancer cells. Therefore, the aim of this review was to further investigate the anticancer activity of secondary metabolites from native and indigenous plants and determine the classes of compounds that contributed towards its activity.
URI: http://hdl.handle.net/10321/3429
ISSN: 2639-0590
DOI: 10.31031/COJRR.2020.02.000545
Appears in Collections:Research Publications (Applied Sciences)

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