Please use this identifier to cite or link to this item: https://hdl.handle.net/10321/3400
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dc.contributor.authorPerumal, Amandaen_US
dc.contributor.authorKrishna, Suresh Babu Naiduen_US
dc.contributor.authorSershenen_US
dc.contributor.authorPillay, Karenen_US
dc.contributor.authorGovender, Patricken_US
dc.date.accessioned2020-06-10T12:55:05Z-
dc.date.available2020-06-10T12:55:05Z-
dc.date.issued2020-05-10-
dc.identifier.citationPerumal, A., Naidu Krishna, S.B., Sershen, Pillay, K., Govender, P. 2020. Phytochemical composition and biological investigation of Trichilia emetica Vahl. seed extracts. Letters in Applied NanoBioScience. 9(2): 1111-1116. doi:10.33263/lianbs92.11111116en_US
dc.identifier.issn2284-6808 (Online)-
dc.identifier.urihttp://hdl.handle.net/10321/3400-
dc.description.abstractThe current study investigated the phytochemical analysis, chemical composition, antioxidant, cytotoxic and antifungal activity of Trichilia emetica seed extracts. Preliminary phytochemical screening and quantification were realized by GC-MS. Consecutive extractions (methanol, ethanol, ethyl acetate, hexane, chloroform and distilled water) were carried out and phytochemical tests performed to represent the variety of phytochemicals. Seed extracts variably displayed alkaloids, cardiac glycosides, phenols, sterols, terpenoids and flavonoids but there was no indication of saponins and tannins in all extracts. The biological investigation of the methanolic extract showed significant biological activities. The results obtained revealed that methanol extract has presented significant IC50 =5.94 µg/mL radical scavenging activity. Minimum inhibitory concentration (MIC) of hexane and chloroform fractions displayed antifungal activity (40.95-100 and 76.27-100.11, respectively) against all three fungal pathogens, whilst the methanol extract inhibited C. krusei and C. parapsilosis and the ethyl acetate inhibited C. parapsilosis only. The results obtained revealed the medicinal importance of the plant and methanol extract of T. emetica would aid researchers to exploit as potential antifungal and antioxidant agent.</jats:p>en_US
dc.description.sponsorshipNational Research Foundation (South Africa)en_US
dc.description.sponsorshipUniversity of KwaZulu-Natal, Durban.en_US
dc.format.extent6 p.en_US
dc.language.isoenen_US
dc.publisherAMG Transcend Associationen_US
dc.relation.ispartofLetters in Applied NanoBioScience; Vol. 9, Issue 2en_US
dc.subjectAnti-oxidanten_US
dc.subjectAntifungalen_US
dc.subjectGC MSen_US
dc.subjectMethanol extracten_US
dc.subjectTrichiliaen_US
dc.titlePhytochemical composition and biological investigation of Trichilia emetica Vahl. seed extractsen_US
dc.typeArticleen_US
dc.date.updated2020-05-19T18:04:01Z-
dc.identifier.doi10.33263/lianbs92.11111116-
local.sdgSDG03-
item.cerifentitytypePublications-
item.languageiso639-1en-
item.grantfulltextopen-
item.openairetypeArticle-
item.fulltextWith Fulltext-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
Appears in Collections:Research Publications (Applied Sciences)
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