Please use this identifier to cite or link to this item: http://hdl.handle.net/10321/1178
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dc.contributor.authorJinabhai, Champaklall-
dc.contributor.authorTathiah, Nerisha-
dc.contributor.authorParboosing, Raveen-
dc.contributor.authorSingh, Lavanya-
dc.contributor.authorMoodley, Pravi-
dc.date.accessioned2015-01-14T12:44:13Z-
dc.date.available2015-01-14T12:44:13Z-
dc.date.issued2013-08-22-
dc.identifier.citationTathiah, N.; Parboosing, R.; Singh, L.; Jinabhai, C.C. and Moodley, P. 2014. Human immunodeficiency virus and hepatitis B or C co-infection in KwaZulu-Natal: a retrospective analysis of a laboratory database. Southern African Journal of Infectious Diseases;29(1):19-22en_US
dc.identifier.issn1015-8722-
dc.identifier.urihttp://hdl.handle.net/10321/1178-
dc.description.abstractHepatitis B or C virus infection has an important influence on treatment and outcomes in human immunodeficiency virus (HIV)-infected individuals. HIV worsens the prognosis in hepatitis B- or C virus-infected patients, and patients on antiretroviral therapy are more likely to experience hepatotoxicity if they are co-infected with a hepatotropic virus. There is a paucity of data on the epidemiology of hepatotropic viruses in relation to each other and to HIV in KwaZulu-Natal. The aim of this study was to describe the seroprevalence of hepatitis B and C virus in HIV-positive and -negative individuals in KwaZulu-Natal from 2002-2010, using a large laboratory database of routine serological results. Patients who had an HIV or hepatitis B or C test performed at the National Health Laboratory Service Department of Virology in Durban from 2002-2010 were included in the study. The study revealed that the overall seropositivity of hepatitis B surface antigen (HBsAg) was 12.05%, and that of hepatitis C immunoglobulin G (IgG), 4.13%. Individuals who were seropositive for HIV had 3.19-fold increased odds of being positive for HBsAg, 2.06-fold increased odds of being hepatitis B virus e antigen-positive, and 2.91-fold increased odds of being hepatitis C virus IgG-positive. Of those individuals who were tested for HBsAg and hepatitis C virus IgG (irrespective of HIV status), 15.76% were seropositive for both markers. HIV-positive individuals are at increased odds of having markers for hepatitis B and C infection.en_US
dc.format.extent4 pen_US
dc.language.isoenen_US
dc.publisherSAJEIen_US
dc.subjectHepatitisen_US
dc.subjectHIVen_US
dc.subjectHepatitis Ben_US
dc.subjectHepatitis Cen_US
dc.subjectCo-infectionen_US
dc.subjectSouth Africaen_US
dc.titleHuman immunodeficiency virus and hepatitis B or C co-infection in KwaZulu-Natal: a retrospective analysis of a laboratory databaseen_US
dc.typeArticleen_US
dc.publisher.urihttp://www.sajei.co.za/index.php/SAJEI/article/view/560en_US
dc.dut-rims.pubnumDUT-004339en_US
item.grantfulltextopen-
item.fulltextWith Fulltext-
Appears in Collections:Research Publications (Health Sciences)
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