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Title: Synthesis, characterization and biological study of novel heterocyclic compounds
Authors: Patel, Nidhi
Bux, Faizal 
Vyavahare, Lochan Vishwas
Singh, Arun
Keywords: 3-hydroxybenzofuran-2-carbohydrazide;azetidinone;Antibacterial activity
Issue Date: 2013
Journal: Der pharmacia lettre ItemCrisRefDisplayStrategy.journals.deleted.icon
Abstract: 3-hydroxybenzofuran-2-carbohydrazide (2) undergoes facile condensation with aromatic aldehydes to afford the corresponding N-arylidene-3-hydroxybenzofuran-2-carbohydrazide (3a-e) in good yields. Cyclo condensation of compounds (3a-e) with chloro acetyl chloride yields N-(3-chloro-2-oxo-4-arylazetidin-1-yl)-3-hydroxybenzofuran-2-carboxamide (4a-e). The structures of these compounds were established on the basis of analytical and spectral data. The newly synthesized compounds were evaluated for their antibacterial and antifungal activities.
ISSN: 0975-5071
Appears in Collections:Research Publications (Water and Wastewater Technology)

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