Please use this identifier to cite or link to this item: http://hdl.handle.net/10321/2293
Title: Synthesis and characterization of Ethyl 7-Acetyl-2-substituted 3-(substituted benzoyl)indolizine-1-carboxylates for in vitro anticancer activity
Authors: Sandeep, C. 
Padmashali, Basavaraj 
Kulkarni, Rashmi S.
Venugopala, Katharigatta Narayanaswamy 
Venugopala, Rashmi 
Odhav, Bharti 
Keywords: Anticancer;Characterization;Indolizine analogues;Synthesis
Issue Date: 2016
Publisher: Chemic Publishing Company
Source: Sandeep, C.. et al. 2016. Synthesis and characterization of Ethyl 7-Acetyl-2-substituted 3-(substituted benzoyl)indolizine-1-carboxylates for in vitro anticancer activity. Asian Journal of Chemistry. 28(5): 1043-1048.
Journal: Asian Journal of Chemistry ItemCrisRefDisplayStrategy.journals.deleted.icon
Abstract: Efficient synthesis of a series of novel indolizines (2a-r) has been achieved by reaction between 4-acetyl-1-[2-(substituted phenyl)-2-oxoethyl]pyridin-1-ium bromide and substituted alkynes in presence of anhydrous potassium carbonate in dimethyl formamide medium. The title compounds have been characterized by spectroscopic techniques and elemental analysis. Selected compounds 2b, 2h, 2i, 2q and 2r have been screened for in vitro anticancer activity using adriamycin as positive control and it was found that compounds 2b, 2q and 2r have shown significant anticancer activity.
URI: http://hdl.handle.net/10321/2293
ISSN: 0970-7077
Appears in Collections:Research Publications (Health Sciences)

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