Please use this identifier to cite or link to this item: http://hdl.handle.net/10321/1100
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dc.contributor.authorRajagopaul, Althea
dc.contributor.authorReddy, Poovendhree
dc.contributor.authorKistnasamy, Emilie Joy
dc.date.accessioned2014-07-15T09:50:38Z
dc.date.available2014-07-15T09:50:38Z
dc.date.issued2014
dc.identifier.citationRajagopaul, A.; Kistnasamy, E.J. and Reddy, P. 2014. Predictors of tuberculosis treatment defaulting in informal dwellers within the eThekwini Municipality, KwaZulu-Natal. Southern African Journal of Infectious Diseases. FIDSSA. 29(1): 27-32.en_US
dc.identifier.issn2312-0053
dc.identifier.urihttp://hdl.handle.net/10321/1100
dc.description.abstractGlobally, tuberculosis causes more than 2-million deaths annually. Despite the implementation of the directly observed treatment strategy (DOTS) in South Africa, cure and defaulter rates have not reached World Health Organization (WHO) target rates. This causes concern as it may increase the risks of the development of multiple drug-resistant tuberculosis. Prior to commencement of this study, the eThekwini Municipality reported a defaulter rate of 18.9% in 2007 and 29% in 2009, which is higher than the WHO guideline of 5%. In 2011, eThekwini reported a defaulter rate of 24.3%. Given these statistics and the impact that these high rates may have on susceptible populations and an already overburdened health system, this study aimed to investigate predictors of defaulting in informal dwellers of eThekwini Municipality, KwaZulu-Natal. The study population comprised 102 defaulters and 102 non-defaulters from informal settlements within eThekwini. It was a cross-sectional descriptive study. The Prince Cyril Zulu Communicable Disease Centre electronic tuberculosis register was used to trace defaulters who were interviewed from informal settlements. Demographic data for non-defaulters were matched from the Prince Cyril Zulu Communicable Disease Centre electronic tuberculosis register, but were not physically traced. A questionnaire was administered to all defaulters and retrospective data were obtained from the Prince Cyril Zulu Communicable Disease Centre register for non-defaulters. Multivariate logistic analysis found smoking, alcohol use and having a family member with tuberculosis to be statistically significant predictors of defaulting. Smoking [odds ratio (OR): 2.79, 95% confidence interval (CI): 1.15, 6.77, p-value ≤ 0.005], alcohol consumption (OR: 7.04, 95% CI: 2.96, 16.71, p-value ≤ 0.005), and having a family history of tuberculosis (OR: 4.60, 95% CI: 2.34, 9.04, p-value = 0.01), were all significantly associated with defaulting in informal dwellers. Smoking, alcohol use and having a family member with tuberculosis were predictors that informal dwellers would default from their treatment. These factors should be included in tuberculosis management programmes.en_US
dc.format.extent6 pen_US
dc.language.isoenen_US
dc.publisherFIDSSAen_US
dc.relation.ispartofSouthern African journal of infectious diseases-
dc.subjectTuberculosisen_US
dc.subjectTreatmenten_US
dc.subjectKwaZulu Natalen_US
dc.titlePredictors of tuberculosis treatment defaulting in informal dwellers within the eThekwini Municipality, KwaZulu-Natalen_US
dc.typeArticleen_US
dc.publisher.urihttp://www.sajei.co.za/index.php/SAJEI/article/view/502en_US
dc.dut-rims.pubnumDUT-004035en_US
item.grantfulltextopen-
item.languageiso639-1other-
item.fulltextWith Fulltext-
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